

Threads
Harmonizing vaccine studies
Out today — my piece in @nature on a topic I feel very strongly about = the need to coordinate and harmonize observational vaccine studies! If you think it is hard to compare vaccine trials, you haven't seen anything yet.
— Natalie E. Dean, PhD (@nataliexdean) March 3, 2021
A thread. 1/6https://t.co/BE7TPXRreg
Turnaround in cases
THINK LIKE AN EPIDEMIOLOGIST: Lately I have been asked why we are seeing a dramatic turnaround in cases in the US. Is it vaccines? Herd immunity? An artifact due to a drop in testing? Behavior change? Weather?? A few tweets about how I step through this question. 1/6 pic.twitter.com/AJ12wvFPX2
— Natalie E. Dean, PhD (@nataliexdean) February 17, 2021
The test negative design
How do we measure how well the flu vaccine works every year? We use an observational study called the "test negative design." A few tweets on how it works, and why it will be a big part of ongoing COVID-19 vaccine evaluation. 1/8
— Natalie E. Dean, PhD (@nataliexdean) February 15, 2021
Figure source: Fukushima et al. (2017) Vaccine pic.twitter.com/7saSMWA9bb